[Mristudio-users] update of gradient table in DtiStudio

HUA KEGANG khua1 at jhu.edu
Tue Dec 28 11:45:35 EST 2010


Hi, Luca
 
The MI algorithm optimizes the normalized mutual information.
 
Thanks! 

KEGANG(LUKE) HUA
Department of Radiology
Johns Hopkins University School of Medicine
720 Rutland Ave Traylor217
Baltimore, MD, 21205



 
> Date: Mon, 27 Dec 2010 09:38:00 +0100
> From: luca.binotto at unipd.it
> Subject: [Mristudio-users] update of gradient table in DtiStudio
> To: mristudio-users at mristudio.org
> 
> Hello Susumu,
> 
> I would like to know something about the way DtiStudio performs the update
> of the gradient table after the realignment of the dti dataset with
> respect to the mean_b0 volume.
> 
> The registration algorithm implemented in DtiStudio using mutual
> information (MI):
> 1) does it uses normalized mutual information or which other formulation ?
> 2) how is the gradient table updated ? (rough simple theory)
> After realignment of the DWI volumes, b-matrix (the gradient table) must
> be updated.
> 
> Patient motion and eddy currents can cause errors in the calculation of
> parameters that describe diffusion in each voxel of a DWI dataset.
> In normal conditions eddy currents contribution should be
> very small (< 1% ?).
> But the b-matrix (gradient table) is calculated with respect to a fixed
> coordinate system (at the acquisition time) so the b-matrix must be
> rotated accordingly to the transformation applied for image registration
> otherwise we should get poor fiber statistics and some fibers possibly
> deviate.
> 
> So the gradient table is affected by rotations. Translations don't
> change it.
> But what does it happen with resampling (applying a scaling factor: es.
> affine transformation) to a dwi dataset?
> According to you is normally its effect small (as for eddy currents
> effect) or can be more important?
> For example a scaling factor such that a volume with a voxel size of
> 2x2x2 mm3 is resliced to a 1x1x1 mm3 voxel size can be important its
> effect or "only" a lower image quality (eg. I read somewhere of a
> "red background" superimposed to the correct color map)?
> 
> 
> thanks in advance,
> best regards,
> 
> Luca
> 
> 
> 
> 
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