[Mristudio-users] DTI & clinical featues of Lewy Body Spectrum Disease Grant

[susanne steinberg]

Dear Dr. Mori and Experts

I am applying for two pilot grants on the subject of the association of
white matter integrity, neuropsychiatric symptoms and  mild neurocognitive
impairment in Lewy Body Dementia and Parkinson's Disease. There has been
much debate whether these diseases are separate entities or whether they are
the actually one disease with variable clinical presentation. This has
prevented us from finding the best biomarker for early diagnosis and
treatment.  I have reviewed the literature on DTI in Lewy Body Spectrum
Diseases, there are some interesting results but there is much more to learn
to answer my research question.

I need help to set up the DTI protocol which could be run at UPenn. I have
been to the MRIStudio but have had no reason to use what I learnt but now I
do. I am also interested in adding a protocol for high angular resolution
imaging. Have you been using that at all? We have wonderful neuroimaging
experts on Aging but not in DTI or HARDI. I think the answers lie in
multimodal approach to imaging (ASL, volumetric MRI and DTI/HARDI)

 

Thanks for considering this request.

Susanne 

 

Susanne Inez Steinberg MD, MBA, MSCE
Director of Geriatric Psychiatrist & Senior Research Associate
Crozer Chester Medical Center & Children's Hospital Of Pennsylvania
One Medical Center Blvd
Philadelphia, PA 19013
Crozer Telephone: 610-874-5257

CHOP Telephone: 267-426-6047

Cell: 215-287-2961
Email: susanne.steinberg at crozer.org

Emai:l  <mailto:susanne.steinberg45 at gmail.com> susanne.steinberg45 at gmail.com

Email: steinbergs1 at email.chop.edu

 

 

From: mristudio-users-bounces at mristudio.org
[mailto:mristudio-users-bounces at mristudio.org] On Behalf Of susumu mori
Sent: Wednesday, December 14, 2011 7:38 AM
To: DTI Studio, ROI Editor, DiffeoMap Questions/Support
Subject: Re: [Mristudio-users] g value

 

Do you mean b-value?

Many simulation studies point 800-1,200 are good numbers.

I prefer a bit lower side like 700. It's personal preference. I like it
because of less motion artifacts and short TE. I came up with this number
based on my subjective experience, but I would say it's safer to use 1,000.

On Wed, Dec 14, 2011 at 2:44 AM, Santosh Yadav <santoshyadav20076 at gmail.com>
wrote:

Hi DTI experts,

 

I was just wondering that what g value (optimum) should be used for making
the bet images in adult population.

 

With regards

 

Santosh



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