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</o:shapelayout></xml><![endif]--></head><body lang=EN-US link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Dear Dr. Mori and Experts<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>I am applying for two pilot grants on the subject of the association of white matter integrity, neuropsychiatric symptoms and mild neurocognitive impairment in Lewy Body Dementia and Parkinson’s Disease. There has been much debate whether these diseases are separate entities or whether they are the actually one disease with variable clinical presentation. This has prevented us from finding the best biomarker for early diagnosis and treatment. I have reviewed the literature on DTI in Lewy Body Spectrum Diseases, there are some interesting results but there is much more to learn to answer my research question.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>I need help to set up the DTI protocol which could be run at UPenn. I have been to the MRIStudio but have had no reason to use what I learnt but now I do. I am also interested in adding a protocol for high angular resolution imaging. Have you been using that at all? We have wonderful neuroimaging experts on Aging but not in DTI or HARDI. I think the answers lie in multimodal approach to imaging (ASL, volumetric MRI and DTI/HARDI)<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thanks for considering this request.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Susanne <o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>Susanne Inez Steinberg MD, MBA, MSCE<br>Director of Geriatric Psychiatrist & Senior Research Associate<br>Crozer Chester Medical Center & Children's Hospital Of Pennsylvania<br>One Medical Center Blvd<br>Philadelphia, PA 19013<br>Crozer Telephone: 610-874-5257<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>CHOP Telephone: 267-426-6047<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>Cell: 215-287-2961<br>Email: susanne.steinberg@crozer.org<o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>Emai:l <a href="mailto:susanne.steinberg45@gmail.com"><span style='color:#1F497D'>susanne.steinberg45@gmail.com</span></a><o:p></o:p></span></p><p class=MsoNormal><span style='color:#1F497D'>Email: steinbergs1@email.chop.edu<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0in 0in 0in'><p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> mristudio-users-bounces@mristudio.org [mailto:mristudio-users-bounces@mristudio.org] <b>On Behalf Of </b>susumu mori<br><b>Sent:</b> Wednesday, December 14, 2011 7:38 AM<br><b>To:</b> DTI Studio, ROI Editor, DiffeoMap Questions/Support<br><b>Subject:</b> Re: [Mristudio-users] g value<o:p></o:p></span></p></div><p class=MsoNormal><o:p> </o:p></p><p class=MsoNormal>Do you mean b-value?<o:p></o:p></p><div><p class=MsoNormal>Many simulation studies point 800-1,200 are good numbers.<o:p></o:p></p></div><div><p class=MsoNormal style='margin-bottom:12.0pt'>I prefer a bit lower side like 700. It's personal preference. I like it because of less motion artifacts and short TE. I came up with this number based on my subjective experience, but I would say it's safer to use 1,000.<o:p></o:p></p><div><p class=MsoNormal>On Wed, Dec 14, 2011 at 2:44 AM, Santosh Yadav <<a href="mailto:santoshyadav20076@gmail.com">santoshyadav20076@gmail.com</a>> wrote:<o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>Hi DTI experts,<o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><o:p> </o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>I was just wondering that what g value (optimum) should be used for making the bet images in adult population.<o:p></o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'><o:p> </o:p></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto'>With regards<o:p></o:p></p><div><p class=MsoNormal><o:p> </o:p></p></div><div><p class=MsoNormal><span style='color:#888888'>Santosh<o:p></o:p></span></p></div><p class=MsoNormal style='margin-bottom:12.0pt'><span style='color:#888888'><br></span><br>_______________________________________________<br>mristudio-users mailing list<br><a href="mailto:mristudio-users@mristudio.org">mristudio-users@mristudio.org</a><br><a href="http://lists.mristudio.org/mailman/listinfo/" target="_blank">http://lists.mristudio.org/mailman/listinfo/</a><br>Unsubscribe, send a blank email to: <a href="mailto:mristudio-users-unsubscribe@mristudio.org">mristudio-users-unsubscribe@mristudio.org</a><o:p></o:p></p></div><p class=MsoNormal><o:p> </o:p></p></div></div></body></html>