[Mristudio-users] DTI Studio in cervical spine

[Dresner, Alex]

This journal article uses DTI Studio for cervical spine:

http://www.mrijournal.com/article/S0730-725X(09)00141-6/abstract
(copied below).

Magnetic Resonance Imaging Volume 28, Issue 1, Pages 70-76 (January 2010)

Dependence of the fractional anisotropy in cervical spine from the
number of diffusion gradients, repeated acquisition and voxel size

Received 26 September 2008; received in revised form 15 May 2009;
accepted 19 May 2009. published online 06 July 2009.

Abstract

The aim of this study is to investigate the consequences of using
different gradient schemes, number of repeated measurements and voxel
size on the fractional anisotropy (FA) value in a diffusion tensor
imaging (DTI) sequence on the cervical tract of the spinal cord.
Twenty healthy volunteers underwent a total of 86 DTI axial
acquisitions performed by using different voxel size and number of
diffusion gradient directions (NDGDs). Three different diffusion
gradient schemes were applied, named 6, 15 and 32 according to the
NDGD. Furthermore, some acquisitions were repeated to investigate the
effects of image averaging on FA value.

Our results indicate that the FA value in the cervical spinal cord
decreases when increasing the NDGD for a fixed spatial resolution, or
when identical acquisitions are repeated, thus, increasing the
acquisition time. This effect is observed in all subjects without
exceptions, and the differences result statistically significant: the
average FA obtained from 6, 15 and 32 NDGD is 0.84 (range, 0.82-0.87),
0.75 (range, 0.68-0.80) and 0.70 (range, 0.65-0.77), respectively, for
isotropic 8 mm3 voxel size. When varying the spatial resolution in a
volume range of 2 to 8 mm3 for a fixed NDGD (6 or 15), the differences
in FA values are smaller albeit still statistically significant: the
smaller the voxel, the larger the FA. No significant dependence of the
FA value from the spatial resolution is observed in the 32 NDGD
acquisitions in the studied volume range.

In conclusion, our results indicate that the value of the FA in the
cervical tract of the spinal cord vary with regularity in intrasubject
acquisitions when modifying the NDGD and when repeated acquisitions
are used; these observations confirm that the signal-to-noise ratio
introduces a systematic error in FA measurements that does not allow
simple comparison of quantitative results obtained from separated
studies.


From: mristudio-users-bounces at mristudio.org [mailto:mristudio-users-bounces at mristudio.org] On Behalf Of Sona Saksena
Sent: Tuesday, February 16, 2010 2:24 PM
To: DTI Studio, ROI Editor, Landmarker Questions/Support; susumu mori
Subject: [Mristudio-users] Urgent


Hello,

Can we process the spinal cord DTI of a patient using DTIstudio. Please let me know. If not, please suggest the possible reason.

Any help is highly appreciated.

thnaks

regards
--
Sona

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