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<p class="MsoNormal">This journal article uses DTI Studio for cervical spine:<o:p></o:p></p>
<p class="MsoNormal"><o:p> </o:p></p>
<p class="MsoNormal"><a href="http://www.mrijournal.com/article/S0730-725X(09)00141-6/abstract">http://www.mrijournal.com/article/S0730-725X(09)00141-6/abstract</a><br>
(copied below).<br>
<br>
Magnetic Resonance Imaging Volume 28, Issue 1, Pages 70-76 (January 2010)<br>
<br>
Dependence of the fractional anisotropy in cervical spine from the<br>
number of diffusion gradients, repeated acquisition and voxel size<br>
<br>
Received 26 September 2008; received in revised form 15 May 2009;<br>
accepted 19 May 2009. published online 06 July 2009.<br>
<br>
Abstract<br>
<br>
The aim of this study is to investigate the consequences of using<br>
different gradient schemes, number of repeated measurements and voxel<br>
size on the fractional anisotropy (FA) value in a diffusion tensor<br>
imaging (DTI) sequence on the cervical tract of the spinal cord.<br>
Twenty healthy volunteers underwent a total of 86 DTI axial<br>
acquisitions performed by using different voxel size and number of<br>
diffusion gradient directions (NDGDs). Three different diffusion<br>
gradient schemes were applied, named 6, 15 and 32 according to the<br>
NDGD. Furthermore, some acquisitions were repeated to investigate the<br>
effects of image averaging on FA value.<br>
<br>
Our results indicate that the FA value in the cervical spinal cord<br>
decreases when increasing the NDGD for a fixed spatial resolution, or<br>
when identical acquisitions are repeated, thus, increasing the<br>
acquisition time. This effect is observed in all subjects without<br>
exceptions, and the differences result statistically significant: the<br>
average FA obtained from 6, 15 and 32 NDGD is 0.84 (range, 0.82–0.87),<br>
0.75 (range, 0.68–0.80) and 0.70 (range, 0.65–0.77), respectively, for<br>
isotropic 8 mm3 voxel size. When varying the spatial resolution in a<br>
volume range of 2 to 8 mm3 for a fixed NDGD (6 or 15), the differences<br>
in FA values are smaller albeit still statistically significant: the<br>
smaller the voxel, the larger the FA. No significant dependence of the<br>
FA value from the spatial resolution is observed in the 32 NDGD<br>
acquisitions in the studied volume range.<br>
<br>
In conclusion, our results indicate that the value of the FA in the<br>
cervical tract of the spinal cord vary with regularity in intrasubject<br>
acquisitions when modifying the NDGD and when repeated acquisitions<br>
are used; these observations confirm that the signal-to-noise ratio<br>
introduces a systematic error in FA measurements that does not allow<br>
simple comparison of quantitative results obtained from separated<br>
studies.<o:p></o:p></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D"><o:p> </o:p></span></p>
<p class="MsoNormal"><span style="font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D"><o:p> </o:p></span></p>
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<p class="MsoNormal"><b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif"">From:</span></b><span style="font-size:10.0pt;font-family:"Tahoma","sans-serif""> mristudio-users-bounces@mristudio.org [mailto:mristudio-users-bounces@mristudio.org]
<b>On Behalf Of </b>Sona Saksena<br>
<b>Sent:</b> Tuesday, February 16, 2010 2:24 PM<br>
<b>To:</b> DTI Studio, ROI Editor, Landmarker Questions/Support; susumu mori<br>
<b>Subject:</b> [Mristudio-users] Urgent<o:p></o:p></span></p>
</div>
<p class="MsoNormal"><o:p> </o:p></p>
<div>
<p class="MsoNormal"><br clear="all">
Hello,<o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
<div>
<p class="MsoNormal">Can we process the spinal cord DTI of a patient using DTIstudio. Please let me know. If not, please suggest the possible reason.<o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
<div>
<p class="MsoNormal">Any help is highly appreciated.<o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
<div>
<p class="MsoNormal">thnaks<o:p></o:p></p>
</div>
<div>
<p class="MsoNormal"> <o:p></o:p></p>
</div>
<div>
<p class="MsoNormal">regards<br>
-- <br>
Sona <o:p></o:p></p>
</div>
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