[Mristudio-users] Fornix tractography

[susumu mori]

Hi Rebecca,

The fornix has "Y" shape pathways. The stem part is where the two
projections from each hemisphere merges in the ventricle and goes down
toward the anterior commissure. The branches veer into lateral regions
toward the hippocampus. The stem area is larger (because it is actually two
tracts) and easier to reconstruct. With 2.2 - 2.5 mm resolution, sometimes
you can't reconstruct the tract in the branching section; it may terminate
before it reaches the hippocampus. The best ROIs would be one in the stem
section close to the anterior commissure and the other in the lateral
hippocampal area. If you get the fiber, you can get the very clean fornix
reconstructed. The only problem is that, because these two ROIs are so far
away, you may not get any results in a significant portion of the subjects.
You need good SNR and resolution to get it reconstructed in almost all
subjects. This is because we didn't include fornix in our tractography
protocol paper in NeuroImage. It's not 100% reproducible with 2.2-2.5 mm
resolution and 5 -10 min scan. You can reconstruct the short stretch of the
stem area using CUT operation, which could be a compromise protocol. In this
case, one ROI defines the stem close to the anterior commissure and the
other right before it branches into two pathways.

Susumu

On Fri, Jan 8, 2010 at 3:21 PM, Rebecca L Kozitza
<rebecca.kozitza at duke.edu>wrote:

>
> What is the best method for tracking the fornix (specifically the fimbria)
> using DTI studio?
>
> Thanks,
> Rebecca
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