Hi Rebecca,<br><br>The fornix has "Y" shape pathways. The stem part is where the two projections from each hemisphere merges in the ventricle and goes down toward the anterior commissure. The branches veer into lateral regions toward the hippocampus. The stem area is larger (because it is actually two tracts) and easier to reconstruct. With 2.2 - 2.5 mm resolution, sometimes you can't reconstruct the tract in the branching section; it may terminate before it reaches the hippocampus. The best ROIs would be one in the stem section close to the anterior commissure and the other in the lateral hippocampal area. If you get the fiber, you can get the very clean fornix reconstructed. The only problem is that, because these two ROIs are so far away, you may not get any results in a significant portion of the subjects. You need good SNR and resolution to get it reconstructed in almost all subjects. This is because we didn't include fornix in our tractography protocol paper in NeuroImage. It's not 100% reproducible with 2.2-2.5 mm resolution and 5 -10 min scan. You can reconstruct the short stretch of the stem area using CUT operation, which could be a compromise protocol. In this case, one ROI defines the stem close to the anterior commissure and the other right before it branches into two pathways.<br>
<br>Susumu<br><br><div class="gmail_quote">On Fri, Jan 8, 2010 at 3:21 PM, Rebecca L Kozitza <span dir="ltr"><<a href="mailto:rebecca.kozitza@duke.edu">rebecca.kozitza@duke.edu</a>></span> wrote:<br><blockquote class="gmail_quote" style="border-left: 1px solid rgb(204, 204, 204); margin: 0pt 0pt 0pt 0.8ex; padding-left: 1ex;">
<br><font size="2" face="sans-serif">What is the best method for tracking
the fornix (specifically the fimbria) using DTI studio?</font>
<br>
<br><font size="2" face="sans-serif">Thanks,</font>
<br><font color="#888888"><font size="2" face="sans-serif">Rebecca</font></font><br>_______________________________________________<br>
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