Hello again DTI Experts,<div><br></div><div>I have a group of patients that have suffered trauma to the head that I am putting through the LDDMM pipeline. A problem I ran across during AIR in DiffeoMap is that since the trauma is causing a hematoma in the B0 image, the registration is very poor. On one subject, I performed DiffeoMap AIR using the Mean DWI image and the registration came out pretty good. I am wondering if this is a valid approach to perform AIR registration.</div>
<div><br></div><div>For the LDDMM registration, usually I use the FA and the Trace image to drive the Kimap. However, I think I will get the same poor results. Should I use just the DWI image to drive the LDDMM registration? There would be no need to do "Intensity Normalization" on the DWI image, correct?</div>
<div><br></div><div>Thank you very much,</div><div>Jeff Sadino</div>