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<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Hello,<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p>&nbsp;</o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>The ICBM-152 Atlas that comes from the UCLA web site has
dimensions of 182 x 218 x 182 .&nbsp; Within DTI Studio it is 181 x 217 x
181.&nbsp; There seems to be a single slice &nbsp;difference between both
templates?&nbsp; Where would the single slice need to be added for both
templates to match?<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p>&nbsp;</o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Regards,<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Arun<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p>&nbsp;</o:p></span></p>

<div>

<div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'>

<p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span
style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>
mristudio-users-bounces@mristudio.org
[mailto:mristudio-users-bounces@mristudio.org] <b>On Behalf Of </b>susumu<br>
<b>Sent:</b> 26 January 2009 17:50<br>
<b>To:</b> 'DTI Studio, ROI Editor, Landmarker Questions/Support'<br>
<b>Subject:</b> Re: [Mristudio-users] human brain atlas<o:p></o:p></span></p>

</div>

</div>

<p class=MsoNormal><o:p>&nbsp;</o:p></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>1) Landmarker can normalize your data to ICBM-152. It comes with
the ICBM (including our ICBM-DTI contrasts) and you can doa linear or non-linear
method.</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>2) If you already normalized to the ICBM-152, the first step can be
skipped. Just make sure the following;</span><span style='font-size:10.0pt;
font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; our ICBM-152 has 181x217x181 matrix with 1 mm resolution</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; You can load our ICBM-152 and your normalized images to
Landmarker (or any other software) to make sure that the compatibility of two
ICBM-152 (one you used and the other one implemented in Landmarker and
RoiEditor).</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; Also, all of our software follows the Radiology convention (right
is left). If you find your image is loaded upside down, that is because of the
brain orientation issue. It is a good practice to make sure right-left is
correct in your entire procedure using a subject with some characteristic
asymmetry</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>3) Once you confirm that your ICBM atlas was compatible with the
one implemented in our software, do the following;</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; Load your normalized data. If you have lesion volume data (I
assume it is 1/0 binary data), load it with some anatomical image such as T2.</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; Make sure that the image dimension is 181x217x181 / 1mm</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; Then, choose &quot;ICBM&quot; as an atlas in the right column</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; There is a button looks like the lung. Click it. This
automatically segment your data into many white matter and gray matter regions
and give you a report. For your lesion image, you can get how many &quot;1 =
lesion pixel&quot; are in each segmented white matter area.</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>&gt; If you want to see the segmentation visually, use the
&quot;load&quot; button in the &quot;atlas&quot; section and load one of the
&quot;WMPM&quot;. You can visually see the superimiposition of the segmentation
on the loaded images.</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>&nbsp;<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:blue'>Try</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p>&nbsp;</o:p></span></p>

<div class=MsoNormal align=center style='text-align:center'><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>

<hr size=2 width="100%" align=center>

</span></div>

<p class=MsoNormal style='margin-bottom:12.0pt'><b><span style='font-size:10.0pt;
font-family:"Tahoma","sans-serif"'>From:</span></b><span style='font-size:10.0pt;
font-family:"Tahoma","sans-serif"'> mristudio-users-bounces@mristudio.org
[mailto:mristudio-users-bounces@mristudio.org] <b>On Behalf Of </b>WangPing<br>
<b>Sent:</b> Monday, January 26, 2009 11:32 AM<br>
<b>To:</b> mristudio-users@mristudio.org<br>
<b>Subject:</b> Re: [Mristudio-users] human brain atlas<br>
<b>Importance:</b> High</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:10.0pt;
font-family:"Verdana","sans-serif"'>Susumu,<br>
<br>
I just played with RoiEditor for a while, and found the atlas with the
software.&nbsp; I am wondering if the tool (or you may recommend other tool)
can use the atlas to label my subjects.&nbsp; Right now my subjects have been
normalized to MNI152 space (non-linear registration), there are white matter
lesions on some subjects, I want to calculate the lesion volume on the white
matter regions.&nbsp; IF I can label my subjects, I will know the lesion volume
on each parcellation. I do not have to need a very detailed label atlas at this
point, maybe a atlas that can divide a brain into a few parcellations will be
okay.<br>
Thanks, any suggestion is&nbsp; high appreciated.<br>
Best Regards,<br>
Ping<br>
<br>
Date: Sun, 25 Jan 2009 08:38:18 -0500<br>
From: susumu@mri.jhu.edu<br>
To: mristudio-users@mristudio.org<br>
Subject: Re: [Mristudio-users] human brain atlas<o:p></o:p></span></p>

<div>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:navy'>Hi Ping,</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>&nbsp;<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:navy'>We have several white matter atlases in lbam.med.jhmi.edu, but the
easiest way is to download Landmarker/RoiEditor from <a
href="http://www.mristudio.org/">www.mristudio.org</a>, which come with
different types of electronic atlases. One of them is population-averaged atlas
in the MNI coordinates. If you use linear normalization, I recommend using this
atlas (named ICBM_DTI-81 for GE/Siemens and JHU-MNI-GA for Philips). If you use
highly non-linear normalization, I recommend the single-subject atlas (named
JHU-MNI-SS). Both atlases come with a hand-segmented white matter parcellation
map (WMPM). If you download RoiEditor, this software can apply the WMPM for
various types of image quantification. Please refer to <a
href="http://www.mristudio.org/">www.mristudio.org</a> for more info.</span><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>&nbsp;<o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Arial","sans-serif";
color:navy'>Susumu</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>&nbsp;<o:p></o:p></span></p>

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<div class=MsoNormal align=center style='text-align:center'>

<hr size=2 width="100%" align=center>

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<p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>From:</span></b><span
style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>
mristudio-users-bounces@mristudio.org [mailto:mristudio-users-bounces@mristudio.org]
<b>On Behalf Of </b>WangPing<br>
<b>Sent:</b> Saturday, January 24, 2009 11:53 PM<br>
<b>To:</b> mristudio-users@mristudio.org<br>
<b>Subject:</b> [Mristudio-users] human brain atlas<br>
<b>Importance:</b> High</span><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'><o:p></o:p></span></p>

</div>

<p class=MsoNormal><span style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>&nbsp;<o:p></o:p></span></p>

<p class=MsoNormal style='margin-bottom:12.0pt'><span style='font-size:10.0pt;
font-family:"Verdana","sans-serif"'>Dear Dr. Mori and the List:<br>
&nbsp;<br>
Could anyone recommend a brain atlas (label atlas) that covers the
main&nbsp;white matters?&nbsp; It will be great if this atlas is easy to
register to MNI template.<br>
&nbsp;<br>
Thanks a lot!<br>
Ping<br>
<br>
<o:p></o:p></span></p>

<div class=MsoNormal align=center style='text-align:center'><span
style='font-size:10.0pt;font-family:"Verdana","sans-serif"'>

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</span></div>

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