[Mristudio-users] Threshold and algorithm advantages for LDDMM

Susumu Mori smoriw at gmail.com
Wed Sep 11 21:20:19 EDT 2013


On Mon, Sep 9, 2013 at 1:39 PM, Dorian P. <alb.net at gmail.com> wrote:

> Dear developers,
>
> In a recent paper from Ceritoglu et al. "Computational analysis of LDDMM
> for brain mapping" it seems like sequential thresholds in LDDMM can speed
> the calculation process. Is this the case, does adding three thresholds
> (0.05 0.01 0.004) be faster than adding only one (0.004)?
>

I forwarded this this question to Can.


>
> Second, my understanding is that LDDMM is better for DTI processing than
> other normalization algorithms (i.e. the one SPM uses). Is there any
> empiric comparison of this, is LDDMM better (at single or dual channels)?
>

Well, if you ask this question, I would say LDDMM is better, but if you ask
the same question to Dr. Ashburner, you may get a different answer. I
believe both LDDMM and Dartel/SPM share a similar deffeomorphic
transformation theory. So, I assume the similar performance. Both should be
better than pre-Dartel transformation methods SPM was offering, but it's
just my guess. There are some unique functions in our LDDMM such as
cascading elasticity controls and multi-contrast simultaneous registration,
both have significant impact on accuracy, but there may be similar
functions in Dartel/SPM by now

>
> Thank you.
>
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