[Mristudio-users] entire structure/track or partial structure/track

[Santosh Yadav]

Dear Dr. Susumu,

Thanks a lot for explaining my query.

With best Regards,

Santosh


On Sat, Apr 6, 2013 at 8:15 AM, susumu mori <susumu at mri.jhu.edu> wrote:

> Hi Santosh,
>
> I want to explain the way we define white matter structures.
> First, let me use the analogy to geological maps. If you open a map of
> your city, there are two types of information; city and county boundaries
> and roads. The former is defined by locations and boundaries. The latter,
> say Route 40, doesn't belong to any specific locations.
>
> When we define white matter structures, one way is based on locations.
> Many classical names of white matter structures are based on locations. For
> example, the posterior limb of the internal capsule is the white matter
> region between the thalamus and the putamen/GP. Our BPM is based on this
> type of  classical "location" definitions of various WM and GM structures.
> Of course, many structures with specific names, such as the corona radiata,
> do not have clear definitions about their boundaries. So, we had to use our
> best, but subjective judgment. Once, somehow, boarders are defined, you can
> use the BPM as a criteria to reproducibly define the structures.
>
> To answer your question, the BPM defines almost the entire brain WM into
> one of the labels.
>
> Another way to define WM structures is based on tractography. This is
> similar to the road information in a map. For example, we can define the
> corticospinal tract (CST) that connects the motor cortex and the brainstem.
> The resultant streamline pass through the corona radiata, the internal
> capsule, the cerebral peduncle, but it doesn't belong to any of these.
>
> If we consider both BPM and tractography are the tools to define ROIs, we
> have two different ways to group voxels inside the WM. Depending on the
> brain abnormality, one way could be more sensitive than the other.
>
> In our atlas, more than 50 "routes" are predefined based on tractography
> results of 20 - 30 normal subjects. You can use them as ROIs, just like you
> use the BMP as ROIs. This tractography-based "route" ROIs, however, do not
> cover the entire brain.
>
> Susumu
>
>
>
>
> On Wed, Mar 27, 2013 at 8:02 PM, Santosh Yadav <
> santoshyadav20076 at gmail.com> wrote:
>
>> Hi MRIStudio experts,
>>
>> I have one question regarding JhuMniSSTypeIIROI map. Is this ROI map
>> includes the entire structure/track or partial structure/track for
>> quantification of DTI matrices, for corticospinal tract and fornix?
>>
>>
>> With best Regards,
>>
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-- 
With Best Regards,

Neuroscience and MR Research Program

Department of Medicine, Queen's Medical Center

University of Hawaii

1356 Lusitana Street, 7th Floor, Honolulu, HI 96813

Phone No. 808-220-7152

Fax No.  808-545-8970
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