[Mristudio-users] transverse diffusion parameters

Shaimaa Abdelsattar shaimaa96 at hotmail.com
Thu Mar 7 00:27:33 EST 2013


Hi,
After ADC calculations, I found ADC map corresponding to each gradient, how can I find one averaged ADC to measure ADC in a specific ROI ?
Another question, please, what is meant by color map o, 1, and 2

Thank you for your efforts


On Mar 7, 2013, at 3:47 AM, "susumu mori" <susumu at mri.jhu.edu> wrote:

> I think it doesn't make too much sense to go below 0.15 for FA threshold. As FA goes down, the fiber orientation has less meaning; there is no orientation for a sphere and because of noise, even perfectly sphere media could be FA = 0.1.
> 
> I think Cut is a better approach. Trajectory in between two ROIs has a strong anatomical constraint and has very small false positive.
> 
> If you are interested in transverse diffusivity, you can use (Evalue1+Evalue2)/2. (assuming 3 Evalues are numbered 0, 1, 2).
> 
> 2DFA2-3 and FA1-3 are metrics to measure difference between Evalue1 and 2 and Evalue0 and 2. We calculate them, but honestly, I'm not sure if it has much meaning.
> 
> 
> 
> On Wed, Mar 6, 2013 at 12:46 PM, Prachi Dubey <pxd2010 at gmail.com> wrote:
>> 
>> Thank you Hangyi thats very helpful.
>>  
>> Do you propose it is best to stick to 0.2 threshold? or there is another lower but reliable threshold. My priorty is to get the most reproducible results for mean tract diffusion parameters.
>>  
>> also what do you think will be more reliable for quantitative purposes, using cut function to exclude the fiber edge or using the entire tract.
>>  
>> Also would like to hear your comments on eigen value1 and 2 and 2DFA2-3 and 2DFA1-3. And how these are computed, how specifically they differ from FA and Trace.
>>  
>> Prachi
>> On Wed, Mar 6, 2013 at 12:36 PM, Hangyi Jiang <hjiang at jhmi.edu> wrote:
>>> 
>>> personally,  I think 0.1 is too low to get reliable (or consistent) fiber tracking results. 
>>> 
>>> best,
>>> 
>>> hangyi
>>> 
>>> 
>>> From: mristudio-users-bounces at mristudio.org [mristudio-users-bounces at mristudio.org] on behalf of Prachi Dubey [pxd2010 at gmail.com]
>>> Sent: Wednesday, March 06, 2013 12:10 PM
>>> To: DTI Studio, ROI Editor, DiffeoMap Questions/Support
>>> Subject: [Mristudio-users] transverse diffusion parameters
>>> 
>>> Hi,
>>>  
>>> Any thoughts on how low one could go on FA threshold for tracking without introducing too much noise. I am using FA=0.2, and a lot of my patients have very severely atropic tracts and it is excluding a lot of the data. I can track more fibers if go as low as 0.1 but that makes me worry if I am introducing tracking error.
>>>  
>>> Also what has your experience been with transverse diffusion values, eigen value1 and 2 and 2DFA2-3 and 2DFA1-3. In my dataset they are more sensitive than FA or Trace.
>>>  
>>> Any thoughts, comments appreciated. Prachi
>>> 
>>> -- 
>>>  
>>> Prachi Dubey, MD MPH
>>> ph:4109614841
>>> 
>>> _______________________________________________
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>> 
>> 
>> 
>> 
>> -- 
>>  
>> Prachi Dubey, MD MPH
>> ph:4109614841
>> 
>> _______________________________________________
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>> mristudio-users at mristudio.org
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> 
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