[Mristudio-users] Normalize DTI studies from different scanners

[susumu mori]

I think cross-scanner normalization is a very tricky issue. It is always
related to your effect size. If you are following a stroke patients and
Warrarian degeneration causes 50% FA change, then you can just scan a
couple of subjects in both scanners and show the maximum difference could
be only within 10%. I think this is a valid logic. However, if you can't do
a comparison study like this (e.g. one of the scanners is out of
commission) and you are going after 5% effect size, then you have a very
tough case, especially for publication.

On Fri, Feb 3, 2012 at 8:00 AM, Lucas Lessa <lucas_lessa at yahoo.com.br>wrote:

> Dear friends,
>
> I'm trying to compare the changes in DTI in a case.
> I have several studies from one subject, all of them have DTI, but I can't
> observe changes, probably because of the differences in the studies.
> Some studies were made in Philips Achieva 1,5T and other in a GE HD 1,5T.
> The good thing is that all studies have 33 directions.
> But it's the only similarity.
> Can I normalize these studies?
> Thank you.
>
> Lucas Lessa.
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