[Mristudio-users] Absence of CST in subcortical motor cortex

[Rajagopalan, Venkateswaran]

Dear All,

In our study we tried to evaluate changes in CST between our patient and control groups using DTI metrics. We reconstructed CST using tracography and measured changes in DTI metrics.

We used same protocol for DTI imaging and the DTI images were processed the same way in DTI studio like setting same the FA threshold for tracking in all the subjects, tracts reconstructed using Wakana et al's two ROI approach i.e we placed our first ROI in cerebral peduncle and then the second ROI in subcortical Motor cortex, used cut operation in all the subjects, then similar kind of outlier rejection of bad DW images.By this i mean same processing steps.


The question i have is in some of these patients CST doesn't go all the way up to motor cortex i.e.after reconstruction CST is available only between cerebral peduncle to top of lateral ventricle and after that ( i.e. higher up) CST is absent, this is seen only in some of our patients not in all the cases. Can i attribute this to the disease process or is there somewhere i am making mistake in my image processing steps.

Thanks in advance.

venkat

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